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Dr Katie Harvey

Profile summary

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Professional biography

I am a Lecturer in the School of Life, Health and Chemical Sciences at The Open University (OU), and am also the Biomedical Sciences Qualification Director, a degree that will be starting at the OU soon.

Research interests

My research focusses on:

1. Determining the importance of morphokinetic parameters on embryo viability, and characterising embryo development in species of agricultural importance.

2. Improving methods for research, development, and quality control in in vitro fertilisation (IVF) practices, with an aim to develop a cell-based replacement for the mouse embryos currently used in IVF media manufacture and cryopreservation research. 

3. Working with human IVF clinics to improve practice and success rates.

External collaborations

I collaborate with colleagues from the Unversities of Kent, Greenwich and Essex.


Morphokinetic Profiling Suggests That Rapid First Cleavage Division Accurately Predicts the Chances of Blastulation in Pig In Vitro Produced Embryos (2024)
Hillyear, Lucy M.; Beckitt, Tom; Zak, Louisa J.; Griffin, Darren K.; Harvey, Simon C. and Harvey, Katie E.
Animals, 14, Article 783(5)

Double vitrification and warming of blastocysts does not affect IVF implantation rates, or birth outcomes (2024)
Al Hashimi, B.; Linara-Demakakou, E.; Harvey, S. C.; Harvey, K. E.; Griffin, D.K.; Ahuja, K. and Macklon, N.
Reproductive BioMedicine Online ((Early access))

Sperm morphology differences associated with pig fertility (2022-02-16)
Mandawala, A. A.; Skinner, B. M.; Walling, G. A.; Harvey, K. E. and Harvey, S.C.
bioRxiv, Article 314708

Supplementation of porcine in vitro maturation medium with FGF2, LIF, and IGF1 enhances cytoplasmic maturation in prepubertal gilts oocytes and improves embryo quality (2022)
Serrano Albal, María; Silvestri, Giuseppe; Kiazim, Lucas G.; Vining, Lucy M.; Zak, Louisa J.; Walling, Grant A.; Haigh, Alexandra M.; Harvey, Simon C.; Harvey, Katie and Griffin, Darren K.
Zygote, 30(6) (pp. 801-808)

The role of apoptosis in cryopreserved animal oocytes and embryos (2021-10-01)
Vining, Lucy May; Zak, Louisa J; Harvey, Simon Crawford and Harvey, Katie Evelyn
Theriogenology, 173 (pp. 93-101)

Identification of optimal assisted aspiration conditions of oocytes for use in porcine in vitro maturation: A re‐evaluation of the relationship between the cumulus oocyte complex and oocyte quality (2021-03)
Silvestri, Giuseppe; Rathje, Claudia C.; Harvey, Simon C.; Gould, Rebecca L.; Walling, Grant A.; Ellis, Peter J.I.; Harvey, Katie E. and Griffin, Darren K.
Veterinary Medicine and Science, 7(2) (pp. 465-473)

UV-filter pollution: current concerns and future prospects (2021)
de Miranda, L. L. R.; Harvey, K. E.; Ahmed, A. and Harvey, S. C.
Environmental Monitoring and Assessment, 193, Article 840(12)

Cryopreservation produces limited long-term effects on the nematode Caenorhabditis elegans (2020-02-01)
Stastna, J. J.; Yiapanas, A. D.; Mandawala, A. A.; Fowler, K. E. and Harvey, S. C.
Cryobiology, 92 (pp. 86-91)

Eukaryotic response to hypothermia in relation to integrated stress responses (2020)
Adjirackor, Naki A.; Harvey, Katie E. and Harvey, Simon C.
Cell Stress and Chaperones, 25(6) (pp. 833-846)

The role of chromosome segregation and nuclear organisation in human subfertility (2019)
Fowler, Katie E.; Mandawala, Anjali A. and Griffin, Darren K.
Biochemical Society Transactions, 47(1) (pp. 425-432)

The production of pig preimplantation embryos in vitro: Current progress and future prospects (2018-09)
Fowler, Katie E.; Mandawala, Anjali A.; Griffin, Darren K.; Walling, Grant A. and Harvey, Simon C.
Reproductive Biology, 18(3) (pp. 203-211)

Canine recommended breed weight ranges are not a good predictor of an ideal body condition score (2018)
Smith, E. G.; Davis, K.; Sulsh, L.; Harvey, S. C. and Fowler, K. E.
Journal of Animal Physiology and Animal Nutrition, 102(4) (pp. 1088-1090)

Jurassic spark: Mapping the genomes of birds and other dinosaurs (2018)
Griffin, Darren K.; O'Connor, Rebecca; Romanov, Michael N; Damas, Joana; Farré, Marta; Martell, Henry; Kiazim, Lucas G.; Jennings, Rebecca; Mandawala, Anjali A.; Joseph, Sunitha; Harvey, Katie E.; Slack, Eden A; Allanson, Emily; Ferguson-Smith, Malcolm A.; Barrett, Paul M; Valenzuela, Nicole and Larkin, Denis M.
Comparative Cytogenetics, 12(3) (pp. 322-323)

Upgrading short-read animal genome assemblies to chromosome level using comparative genomics and a universal probe set (2017)
Damas, Joana; O'Connor, Rebecca; Farré, Marta; Lenis, Vasileios Panagiotis E.; Martell, Henry J.; Mandawala, Anjali; Harvey, Katie; Joseph, Sunitha; Swain, Martin T.; Griffin, Darren K. and Larkin, Denis M.
Genome Research, 27(5) (pp. 875-884)

Time-lapse embryo imaging and morphokinetic profiling: Towards a general characterisation of embryogenesis (2016-11)
Mandawala, A.A.; Harvey, S.C.; Roy, T.K. and Fowler, K. E.
Animal Reproduction Science, 174 (pp. 2-10)

Cryopreservation of animal oocytes and embryos: Current progress and future prospects (2016-10-15)
Mandawala, A.A.; Harvey, S.C.; Roy, T.K. and Fowler, K. E.
Theriogenology, 86(7) (pp. 1637-1644)

Multicolor detection of every chromosome as a means of detecting mosaicism and nuclear organization in human embryonic nuclei (2016)
Turner, Kara; Fowler, Katie; Fonseka, Gothami; Griffin, Darren and Ioannou, Dimitrios
Panminerva Medica, 58(2) (pp. 175-90)

Upgrading molecular cytogenetics to study reproduction and reproductive isolation in mammals, birds, and dinosaurs (2016)
O'Connor, Rebecca; Damas, J.; Farré, Marta; Romanov, Michael N.; Martell, Henry; Fonseka, Gothami; Jennings, R.; Kiazam, L.; Bennett, Sophie; Ward, Jake; Mandawala, A.; Joseph, S.; Frodsham, Richard; Lawrie, M.; Archibald, Alan L.; Walling, Grant A.; Fowler, Katie E.; Larkin, Denis M. and Griffin, Darren K.
Cytogenetic and Genome Research, 148(2-3) (pp. 151-152 (Abstract VII.13))

Third Report on Chicken Genes and Chromosomes 2015 (2015-07)
Schmid, Michael; Smith, Jacqueline; Burt, David W.; Aken, Bronwen L.; Antin, Parker B.; Archibald, Alan L.; Ashwell, Chris; Blackshear, Perry J.; Boschiero, Clarissa; Brown, C. Titus; Burgess, Shane C.; Cheng, Hans H.; Chow, William; Coble, Derrick J.; Cooksey, Amanda; Crooijmans, Richard P.M.A.; Damas, Joana; Davis, Richard V.N.; de Koning, Dirk-Jan; Delany, Mary E.; Derrien, Thomas; Desta, Takele T.; Dunn, Ian C.; Dunn, Matthew; Ellegren, Hans; Eöry, Lél; Erb, Ionas; Farré, Marta; Fasold, Mario; Fleming, Damarius; Flicek, Paul; Fowler, Katie E.; Frésard, Laure; Froman, David P.; Garceau, Valerie; Gardner, Paul P.; Gheyas, Almas A.; Griffin, Darren K.; Groenen, Martien A.M.; Haaf, Thomas; Hanotte, Olivier; Hart, Alan; Häsler, Julien; Hedges, S. Blair; Hertel, Jana; Howe, Kerstin; Hubbard, Allen; Hume, David A.; Kaiser, Pete; Kedra, Darek; Kemp, Stephen J.; Klopp, Christophe; Kniel, Kalmia E.; Kuo, Richard; Lagarrigue, Sandrine; Lamont, Susan J.; Larkin, Denis M.; Lawal, Raman A.; Markland, Sarah M.; McCarthy, Fiona; McCormack, Heather A.; McPherson, Marla C.; Motegi, Akira; Muljo, Stefan A.; Münsterberg, Andrea; Nag, Rishi; Nanda, Indrajit; Neuberger, Michael; Nitsche, Anne; Notredame, Cedric; Noyes, Harry; O'Connor, Rebecca; O'Hare, Elizabeth A.; Oler, Andrew J.; Ommeh, Sheila C.; Pais, Helio; Persia, Michael; Pitel, Frédérique; Preeyanon, Likit; Prieto Barja, Pablo; Pritchett, Elizabeth M.; Rhoads, Douglas D.; Robinson, Charmaine M.; Romanov, Michael N.; Rothschild, Max; Roux, Pierre-François; Schmidt, Carl J.; Schneider, Alisa-Sophia; Schwartz, Matthew G.; Searle, Steve M.; Skinner, Michael A.; Smith, Craig A.; Stadler, Peter F.; Steeves, Tammy E.; Steinlein, Claus; Sun, Liang; Takata, Minoru; Ulitsky, Igor; Wang, Qing; Wang, Ying; Warren, Wesley C.; Wood, Jonathan M.D.; Wragg, David and Zhou, Huaijun
Cytogenetic and Genome Research, 145(2) (pp. 78-179)

20th International Chromosome Conference (ICCXX) (2015)
Griffin, Darren K.; Fowler, Katie E.; Ellis, Peter J. I. and Jackson, Dean A.
Chromosome Research, 23(2) (pp. 343-414)

Reconstruction of gross avian genome structure, organization and evolution suggests that the chicken lineage most closely resembles the dinosaur avian ancestor (2014)
Romanov, Michael N; Farré, Marta; Lithgow, Pamela E; Fowler, Katie E.; Skinner, Benjamin M; O’Connor, Rebecca; Fonseka, Gothami; Backström, Niclas; Matsuda, Yoichi; Nishida, Chizuko; Houde, Peter; Jarvis, Erich D; Ellegren, Hans; Burt, David W; Larkin, Denis M and Griffin, Darren K
BMC Genomics, 15, Article 1060(1)

Genome wide analysis reveals single nucleotide polymorphisms associated with fatness and putative novel copy number variants in three pig breeds (2013)
Fowler, Katie E.; Pong-Wong, Ricardo; Bauer, Julien; Clemente, Emily J; Reitter, Christopher P; Affara, Nabeel A; Waite, Stephen; Walling, Grant A and Griffin, Darren K
BMC Genomics, 14, Article 784(1)

Novel approach for deriving genome wide SNP analysis data from archived blood spots (2012)
Fowler, Katie E.; Reitter, Chris P; Walling, Grant A and Griffin, Darren K
BMC Research Notes, 5, Article 503(1)

Analyses of pig genomes provide insight into porcine demography and evolution (2012)
Groenen, Martien A. M.; Archibald, Alan L.; Uenishi, Hirohide; Tuggle, Christopher K.; Takeuchi, Yasuhiro; Rothschild, Max F.; Rogel-Gaillard, Claire; Park, Chankyu; Milan, Denis; Megens, Hendrik-Jan; Li, Shengting; Larkin, Denis M.; Kim, Heebal; Frantz, Laurent A. F.; Caccamo, Mario; Ahn, Hyeonju; Aken, Bronwen L.; Anselmo, Anna; Anthon, Christian; Auvil, Loretta; Badaoui, Bouabid; Beattie, Craig W.; Bendixen, Christian; Berman, Daniel; Blecha, Frank; Blomberg, Jonas; Bolund, Lars; Bosse, Mirte; Botti, Sara; Bujie, Zhan; Bystrom, Megan; Capitanu, Boris; Carvalho-Silva, Denise; Chardon, Patrick; Chen, Celine; Cheng, Ryan; Choi, Sang-Haeng; Chow, William; Clark, Richard C.; Clee, Christopher; Crooijmans, Richard P. M. A.; Dawson, Harry D.; Dehais, Patrice; De Sapio, Fioravante; Dibbits, Bert; Drou, Nizar; Du, Zhi-Qiang; Eversole, Kellye; Fadista, João; Fairley, Susan; Faraut, Thomas; Faulkner, Geoffrey J.; Fowler, Katie E.; Fredholm, Merete; Fritz, Eric; Gilbert, James G. R.; Giuffra, Elisabetta; Gorodkin, Jan; Griffin, Darren K.; Harrow, Jennifer L.; Hayward, Alexander; Howe, Kerstin; Hu, Zhi-Liang; Humphray, Sean J.; Hunt, Toby; Hornshøj, Henrik; Jeon, Jin-Tae; Jern, Patric; Jones, Matthew; Jurka, Jerzy; Kanamori, Hiroyuki; Kapetanovic, Ronan; Kim, Jaebum; Kim, Jae-Hwan; Kim, Kyu-Won; Kim, Tae-Hun; Larson, Greger; Lee, Kyooyeol; Lee, Kyung-Tai; Leggett, Richard; Lewin, Harris A.; Li, Yingrui; Liu, Wansheng; Loveland, Jane E.; Lu, Yao; Lunney, Joan K.; Ma, Jian; Madsen, Ole; Mann, Katherine; Matthews, Lucy; McLaren, Stuart; Morozumi, Takeya; Murtaugh, Michael P.; Narayan, Jitendra; Truong Nguyen, Dinh; Ni, Peixiang; Oh, Song-Jung; Onteru, Suneel; Panitz, Frank; Park, Eung-Woo; Park, Hong-Seog; Pascal, Geraldine; Paudel, Yogesh; Perez-Enciso, Miguel; Ramirez-Gonzalez, Ricardo; Reecy, James M.; Rodriguez-Zas, Sandra; Rohrer, Gary A.; Rund, Lauretta; Sang, Yongming; Schachtschneider, Kyle; Schraiber, Joshua G.; Schwartz, John; Scobie, Linda; Scott, Carol; Searle, Stephen; Servin, Bertrand; Southey, Bruce R.; Sperber, Goran; Stadler, Peter; Sweedler, Jonathan V.; Tafer, Hakim; Thomsen, Bo; Wali, Rashmi; Wang, Jian; Wang, Jun; White, Simon; Xu, Xun; Yerle, Martine; Zhang, Guojie; Zhang, Jianguo; Zhang, Jie; Zhao, Shuhong; Rogers, Jane; Churcher, Carol and Schook, Lawrence B.
Nature, 491(7424) (pp. 393-398)

Comparative genomics in chicken and Pekin duck using FISH mapping and microarray analysis (2009)
Skinner, Benjamin M; Robertson, Lindsay BW; Tempest, Helen G; Langley, Elizabeth J; Ioannou, Dimitris; Fowler, Katie E.; Crooijmans, Richard PMA; Hall, Anthony D; Griffin, Darren K and Völker, Martin
BMC Genomics, 10(1)

Assembling and comparing avian genomes by molecular cytogenetics (2015)
Martell, Henry; O'Connor, Rebecca; Damas, J.; Mandawala, A.; Fowler, Katie E.; Joseph, S.; Farré, Marta; Romanov, Michael N; Lithgow, Pamela E; Larkin, Denis M. and Griffin, Darren K.
In : 2nd Bioinformatics Student Symposium (7 Oct 2015, Norwich, Norfolk) (Abstract B21)